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ePaper created 2017-03-14, 10:25:37 | version 1.49.03
Good laboratory practice (GLP) test facility Several non-clinical tests are running at our category 9 GLP unit (“Cell-based test systems for the determination of bio- logical parameters”) to support research and development projects that investigate biological parameters of samples / substances using cell-based assays. Examples are the testing of bioactivity, cytotoxicity and immunogenicity of compounds using immune receptor-based assays, screening of TLR agonists / antagonists, testing of antimicrobial properties of substances or surfaces, as well as detection of pyrogens and microbial residues (pathogen-associated microbial patterns, PAMPs). Spectrum of services Process and product development Design and construction of demonstration plants and prototypes Implementation of new technologies Licensing of technologies and processes Studies and consultancy Feasibility studies and technology analyses Proitability studies and life cycle assessment High-resolution 400 MHz NMR analysis Molecular structure elucidation, reaction monitoring, develop- ment of novel experimental NMR methods, low-temperature analysis Surface and particle analysis Characterization of chemical, physical and morphological properties of surfaces, thin layers, powders, and particles Microbial evaluation Testing of antimicrobial effects and photocatalytic properties of surfaces Biochemical and biomolecular analysis Diagnostic microarrays, protein expression proiles, protein analysis using MALDI-TOF / TOF mass spectrometry (also quantitative) Next-generation sequencing De novo genome / transcriptome sequencing, meta-genomics and meta-transcriptomics, microbiomics, next generation diagnostics (infectious diseases, COPD, etc.) Cell biology analysis Cell characterization, single cell preparation / microdissection, low cytometry, quality and sterility control of tissue engineer- ing products Analysis and testing services Our broad range of biological and physical / chemical examina- tion methods makes the institute a versatile partner in the ields of medicine and pharmacy, food production and chem- istry as well as environmental and water analysis. Cell-material interactions Testing of cytotoxicity / biocompatibility of R&D materials and industrial products, assessment of phototoxicity of substances and solutions, evaluation and testing of chemicals (REACH) and nanomaterials Physico-chemical analysis Quality control, food analysis, trace analysis, analysis of resi- For detailed information on dues, environmental analysis, water analysis the analytical services we offer, please visit: www.igb.fraunhofer.de/analytics 1 3