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ePaper created 2014-05-07, 13:23:14 | version 1.30.01
71 Eva Brauchle M.Sc. Phone +49 711 970-4196 eva.brauchle@igb.fraunhofer.de Prof. Dr. Katja Schenke-Layland Phone +49 711 970-4802 katja.schenke-layland@ igb.fraunhofer.de which can be identified by specific signals in the Raman spec- trum [4, 5]. The remodeling of matrix components is often associated with pathological conditions. Using Raman spec- troscopy, we examine the extracellular matrix in healthy and diseased tissues. Together with our expertise in immune and histochemical methods, we can correlate these results with our Raman spectra to identify new diagnostic markers. Outlook We are currently developing the Raman technology for intra- operative tumor diagnostic methods. We are also using Ra- man spectroscopy in the field of women’s health in order to analyze different pathologies at the molecular level. 1 Principle of Raman spectroscopy. 2 Raman spectra of stem cells. 3 Raman microscope at the Fraunhofer IGB. References [1] Votteler, M. et al. (2012) J Vis Exp (63), e3977 [2] Brauchle, E. et. al. (2013) Biotechnol J 8(3): 288 – 297 [3] Pudlas, M. et al. (2011) Tissue Eng Part C Methods 17(10): 1027 – 1040 [4] Pudlas, M. et al. (2013) J Biophotonics 6(2): 205 – 211 [5] Votteler, M. et al. (2012) J Biophotonics 5(1): 47 – 56 Funding We would like to thank the Ministry of Science, Research and the Arts Baden-Württemberg for funding the project “Industry on Campus Project of IZST”, grant number IoC 102. Project partners University Hospital for Women of the Eberhard Karls University of Tübingen | IGVP, University of Stuttgart | Queensland Univer- sity of Technology, Australia | University of California Los Ange- les, USA | Beiersdorf AG, Hamburg | ERBE Elektromedizintech- nik GmbH, Tübingen | Karl Storz GmbH & Co. KG, Tuttlingen Further Information www.schenke-layland-lab.com 2 3 Contacts